First-authored paper in Nature Communications by Jia Li
Congratulations to postdoctoral fellow Jia Li, professor and chair Yu Shyr, and professor Qi Liu on the August 22 publication of Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn’s disease (CD) in Nature Communications. Dr. Li is first author of the paper and Dr. Liu its corresponding author. The team's study of terminal ileum and ascending colon (LND) cells in CD patients has led to findings that "suggest a potential pathogenic role" for such cells in inflammatory bowel disease (IBD).
Figure 1 from the paper. Visit it at the publication site for the full caption.
First-authored paper in Genome Biology by Jia Li
Congratulations to postdoctoral fellow Jia Li on the publication of "aKNNO: single-cell and spatial transcriptomics clustering with an optimized adaptive k-nearest neighbor graph" in Genome Biology on August 1, with professors Yu Shyr and Qi Liu as corresponding authors. The paper offers a new method "to simultaneously identify abundant and rare cell types based on an adaptive k-nearest neighbor graph with optimization," doing so "more accurately than general and specialized methods." {aKKNO} and related tutorials are free and available on GitHub and Zenodo.
Figure 1 in the paper provides an overview of how aKNNO works.